EFFICACY AND SAFETY OF LIPID-LOWERING THERAPIES IN COMBINATION WITH OR WITHOUT STATIN TO REDUCE THE CARDIOVASCULAR RISK: A SYSTEMATIC REVIEW OF RANDOMISED CONTROLLED TRIALS

Efficacy and safety of lipid-lowering therapies in combination with or without statin to reduce the cardiovascular risk: A systematic review of randomised controlled trials

Background and aims: Cardiovascular diseases (CVD) pose a significant global health burden.Lowering low-density lipoprotein-cholesterol is the primary therapeutic aim for preventing primary and secondary CVD events.While statins are the standard treatments, their limitations, such as side effects and intolerance in certain patient groups, Bar Spoon

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Completing the Puzzle: A Cluster of Hunting Dogs with Tick-Borne Illness from a Fishing Community in Tobago, West Indies

Eight hunting dogs were visited by a state veterinarian on the island of Tobago, Trinidad and Tobago, West Indies, as owners reported anorexia and paralysis in five of their dogs.The veterinarian observed a combination of clinical signs consistent with tick-borne illness, including fever, anorexia, anaemia, lethargy and paralysis.Blood and ticks we

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Uridine as a novel fuel for cancer cells

Cancer cells are known to have an enormous appetite for calorie.This is something they are addicted to sustain their unrestricted growth and rapid proliferation.In order to accomplish this feat, cancer cells has evolved multiple mechanisms, rewiring their metabolic circuitry such that metabolic fuels are preferentially diverted to meet their energy

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